Compile Data Set for Download or QSAR

Found 93 hits from Imam Abdulrahman Bin Faisal University   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Thymidine phosphorylase (Homo sapiens (Human))	BDBM50274904 (CHEMBL4129617) Show SMILES Br.Clc1c(CN2CCNC2=N)[nH]c(=O)[nH]c1=O Show InChI InChI=1S/C8H10ClN5O2/c9-5-4(12-8(16)13-6(5)15)3-14-2-1-11-7(14)10/h1-3H2,(H2,10,11)(H2,12,13,15,16)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
Imam Abdulrahman Bin Faisal University Curated by ChEMBL					Assay Description Inhibition of thymidine phosphorylase (unknown origin)				Bioorg Med Chem 26: 3654-3663 (2018) Article DOI: 10.1016/j.bmc.2018.05.046 BindingDB Entry DOI: 10.7270/Q22V2JKV
					More data for this Ligand-Target Pair
Thymidine phosphorylase (Homo sapiens (Human))	BDBM20079 (5-chloro-6-[(2-iminopyrrolidin-1-yl)methyl]-1,2,3,...) Show SMILES Clc1c(CN2CCCC2=N)[nH]c(=O)[nH]c1=O Show InChI InChI=1S/C9H11ClN4O2/c10-7-5(12-9(16)13-8(7)15)4-14-3-1-2-6(14)11/h11H,1-4H2,(H2,12,13,15,16)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	35	n/a	n/a	n/a	n/a	n/a	n/a
Imam Abdulrahman Bin Faisal University Curated by ChEMBL					Assay Description Inhibition of human placenta thymidine phosphorylase using [6-3H]dThd as substrate after 5 mins by scintillation counting method				Bioorg Med Chem 26: 3654-3663 (2018) Article DOI: 10.1016/j.bmc.2018.05.046 BindingDB Entry DOI: 10.7270/Q22V2JKV
					More data for this Ligand-Target Pair				3D Structure (crystal)
Beta-glucuronidase (Homo sapiens (Human))	BDBM50284071 (CHEMBL4165927) Show SMILES Cc1ccc(cc1)C(c1c[nH]c2ccc(cc12)C(=O)N\N=C\c1cc(O)c(O)cc1O)c1c[nH]c2ccc(cc12)C(=O)N\N=C\c1cc(O)c(O)cc1O Show InChI InChI=1S/C40H32N6O8/c1-20-2-4-21(5-3-20)38(28-18-41-30-8-6-22(10-26(28)30)39(53)45-43-16-24-12-34(49)36(51)14-32(24)47)29-19-42-31-9-7-23(11-27(29)31)40(54)46-44-17-25-13-35(50)37(52)15-33(25)48/h2-19,38,41-42,47-52H,1H3,(H,45,53)(H,46,54)/b43-16+,44-17+	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
Imam Abdulrahman Bin Faisal University Curated by ChEMBL					Assay Description Inhibition of human beta-glucuronidase				Eur J Med Chem 143: 1757-1767 (2018) Article DOI: 10.1016/j.ejmech.2017.10.071 BindingDB Entry DOI: 10.7270/Q23N25X1
					More data for this Ligand-Target Pair
Beta-glucuronidase (Homo sapiens (Human))	BDBM50284029 (CHEMBL4168635) Show SMILES Cc1ccc(cc1)C(c1c[nH]c2ccc(cc12)C(=O)N\N=C\c1cccc(O)c1O)c1c[nH]c2ccc(cc12)C(=O)N\N=C\c1cccc(O)c1O Show InChI InChI=1S/C40H32N6O6/c1-22-8-10-23(11-9-22)36(30-20-41-32-14-12-24(16-28(30)32)39(51)45-43-18-26-4-2-6-34(47)37(26)49)31-21-42-33-15-13-25(17-29(31)33)40(52)46-44-19-27-5-3-7-35(48)38(27)50/h2-21,36,41-42,47-50H,1H3,(H,45,51)(H,46,52)/b43-18+,44-19+	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
Imam Abdulrahman Bin Faisal University Curated by ChEMBL					Assay Description Inhibition of human beta-glucuronidase				Eur J Med Chem 143: 1757-1767 (2018) Article DOI: 10.1016/j.ejmech.2017.10.071 BindingDB Entry DOI: 10.7270/Q23N25X1
					More data for this Ligand-Target Pair
Urease (Canavalia ensiformis (Jack bean) (Horse bean))	BDBM50452584 (CHEMBL4208211) Show SMILES Cc1ccc(cc1)C(c1c[nH]c2ccc(cc12)C(=O)NNC(=S)Nc1ccc(Cl)c(Cl)c1)c1c[nH]c2ccc(cc12)C(=O)NNC(=S)Nc1ccc(Cl)c(Cl)c1 Show InChI InChI=1S/C40H30Cl4N8O2S2/c1-20-2-4-21(5-3-20)36(28-18-45-34-12-6-22(14-26(28)34)37(53)49-51-39(55)47-24-8-10-30(41)32(43)16-24)29-19-46-35-13-7-23(15-27(29)35)38(54)50-52-40(56)48-25-9-11-31(42)33(44)17-25/h2-19,36,45-46H,1H3,(H,49,53)(H,50,54)(H2,47,51,55)(H2,48,52,56)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	140	n/a	n/a	n/a	n/a	n/a	n/a
Imam Abdulrahman Bin Faisal University Curated by ChEMBL					Assay Description Inhibition of jack bean urease assessed as reduction in ammonia production using urea as substrate after 15 mins by indophenol method				Bioorg Med Chem 26: 152-160 (2018) Article DOI: 10.1016/j.bmc.2017.11.028 BindingDB Entry DOI: 10.7270/Q22N54VJ
					More data for this Ligand-Target Pair
Beta-glucuronidase (Homo sapiens (Human))	BDBM50284055 (CHEMBL4177204) Show SMILES Cc1ccc(cc1)C(c1c[nH]c2ccc(cc12)C(=O)N\N=C\c1c(O)cc(O)cc1O)c1c[nH]c2ccc(cc12)C(=O)N\N=C\c1c(O)cc(O)cc1O Show InChI InChI=1S/C40H32N6O8/c1-20-2-4-21(5-3-20)38(28-16-41-32-8-6-22(10-26(28)32)39(53)45-43-18-30-34(49)12-24(47)13-35(30)50)29-17-42-33-9-7-23(11-27(29)33)40(54)46-44-19-31-36(51)14-25(48)15-37(31)52/h2-19,38,41-42,47-52H,1H3,(H,45,53)(H,46,54)/b43-18+,44-19+	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
Imam Abdulrahman Bin Faisal University Curated by ChEMBL					Assay Description Inhibition of human beta-glucuronidase				Eur J Med Chem 143: 1757-1767 (2018) Article DOI: 10.1016/j.ejmech.2017.10.071 BindingDB Entry DOI: 10.7270/Q23N25X1
					More data for this Ligand-Target Pair
Beta-glucuronidase (Homo sapiens (Human))	BDBM50284072 (CHEMBL4173852) Show SMILES Cc1ccc(cc1)C(c1c[nH]c2ccc(cc12)C(=O)N\N=C\c1ccc(O)c(O)c1)c1c[nH]c2ccc(cc12)C(=O)N\N=C\c1ccc(O)c(O)c1 Show InChI InChI=1S/C40H32N6O6/c1-22-2-6-25(7-3-22)38(30-20-41-32-10-8-26(16-28(30)32)39(51)45-43-18-23-4-12-34(47)36(49)14-23)31-21-42-33-11-9-27(17-29(31)33)40(52)46-44-19-24-5-13-35(48)37(50)15-24/h2-21,38,41-42,47-50H,1H3,(H,45,51)(H,46,52)/b43-18+,44-19+	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
Imam Abdulrahman Bin Faisal University Curated by ChEMBL					Assay Description Inhibition of human beta-glucuronidase				Eur J Med Chem 143: 1757-1767 (2018) Article DOI: 10.1016/j.ejmech.2017.10.071 BindingDB Entry DOI: 10.7270/Q23N25X1
					More data for this Ligand-Target Pair
Beta-glucuronidase (Homo sapiens (Human))	BDBM50284057 (CHEMBL4172421) Show SMILES Cc1ccc(cc1)C(c1c[nH]c2ccc(cc12)C(=O)N\N=C\c1ccc(O)cc1O)c1c[nH]c2ccc(cc12)C(=O)N\N=C\c1ccc(O)cc1O Show InChI InChI=1S/C40H32N6O6/c1-22-2-4-23(5-3-22)38(32-20-41-34-12-8-24(14-30(32)34)39(51)45-43-18-26-6-10-28(47)16-36(26)49)33-21-42-35-13-9-25(15-31(33)35)40(52)46-44-19-27-7-11-29(48)17-37(27)50/h2-21,38,41-42,47-50H,1H3,(H,45,51)(H,46,52)/b43-18+,44-19+	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
Imam Abdulrahman Bin Faisal University Curated by ChEMBL					Assay Description Inhibition of human beta-glucuronidase				Eur J Med Chem 143: 1757-1767 (2018) Article DOI: 10.1016/j.ejmech.2017.10.071 BindingDB Entry DOI: 10.7270/Q23N25X1
					More data for this Ligand-Target Pair
Urease (Canavalia ensiformis (Jack bean) (Horse bean))	BDBM50452571 (CHEMBL4209771) Show SMILES Cc1ccc(cc1)C(c1c[nH]c2ccc(cc12)C(=O)NNC(=S)Nc1ccc(cc1)C(F)(F)F)c1c[nH]c2ccc(cc12)C(=O)NNC(=S)Nc1ccc(cc1)C(F)(F)F Show InChI InChI=1S/C42H32F6N8O2S2/c1-22-2-4-23(5-3-22)36(32-20-49-34-16-6-24(18-30(32)34)37(57)53-55-39(59)51-28-12-8-26(9-13-28)41(43,44)45)33-21-50-35-17-7-25(19-31(33)35)38(58)54-56-40(60)52-29-14-10-27(11-15-29)42(46,47)48/h2-21,36,49-50H,1H3,(H,53,57)(H,54,58)(H2,51,55,59)(H2,52,56,60)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
Imam Abdulrahman Bin Faisal University Curated by ChEMBL					Assay Description Inhibition of jack bean urease assessed as reduction in ammonia production using urea as substrate after 15 mins by indophenol method				Bioorg Med Chem 26: 152-160 (2018) Article DOI: 10.1016/j.bmc.2017.11.028 BindingDB Entry DOI: 10.7270/Q22N54VJ
					More data for this Ligand-Target Pair
Urease (Canavalia ensiformis (Jack bean) (Horse bean))	BDBM50452593 (CHEMBL4202962) Show SMILES Cc1ccc(cc1)C(c1c[nH]c2ccc(cc12)C(=O)NNC(=S)Nc1ccccc1F)c1c[nH]c2ccc(cc12)C(=O)NNC(=S)Nc1ccccc1F Show InChI InChI=1S/C40H32F2N8O2S2/c1-22-10-12-23(13-11-22)36(28-20-43-32-16-14-24(18-26(28)32)37(51)47-49-39(53)45-34-8-4-2-6-30(34)41)29-21-44-33-17-15-25(19-27(29)33)38(52)48-50-40(54)46-35-9-5-3-7-31(35)42/h2-21,36,43-44H,1H3,(H,47,51)(H,48,52)(H2,45,49,53)(H2,46,50,54)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	800	n/a	n/a	n/a	n/a	n/a	n/a
Imam Abdulrahman Bin Faisal University Curated by ChEMBL					Assay Description Inhibition of jack bean urease assessed as reduction in ammonia production using urea as substrate after 15 mins by indophenol method				Bioorg Med Chem 26: 152-160 (2018) Article DOI: 10.1016/j.bmc.2017.11.028 BindingDB Entry DOI: 10.7270/Q22N54VJ
					More data for this Ligand-Target Pair
Beta-glucuronidase (Homo sapiens (Human))	BDBM50510735 (CHEMBL4567565) Show SMILES COc1cc(O)ccc1-c1nnc(o1)-c1ccc(cc1)-c1nnc(s1)-c1c(Cl)cc(Cl)cc1Cl Show InChI InChI=1S/C23H13Cl3N4O3S/c1-32-18-10-14(31)6-7-15(18)21-28-27-20(33-21)11-2-4-12(5-3-11)22-29-30-23(34-22)19-16(25)8-13(24)9-17(19)26/h2-10,31H,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	960	n/a	n/a	n/a	n/a	n/a	n/a
Imam Abdulrahman Bin Faisal University Curated by ChEMBL					Assay Description Inhibition of human beta-glucuronidase pre-incubated for 30 mins before p-nitrophenyl-beta-D-glucuronide substrate addition by spectrophotometry				Bioorg Med Chem 27: 3145-3155 (2019) Article DOI: 10.1016/j.bmc.2019.05.049 BindingDB Entry DOI: 10.7270/Q2DR2ZVG
					More data for this Ligand-Target Pair
Urease (Canavalia ensiformis (Jack bean) (Horse bean))	BDBM50452582 (CHEMBL4214144) Show SMILES Cc1ccc(cc1)C(c1c[nH]c2ccc(cc12)C(=O)NNC(=S)Nc1cccc(F)c1)c1c[nH]c2ccc(cc12)C(=O)NNC(=S)Nc1cccc(F)c1 Show InChI InChI=1S/C40H32F2N8O2S2/c1-22-8-10-23(11-9-22)36(32-20-43-34-14-12-24(16-30(32)34)37(51)47-49-39(53)45-28-6-2-4-26(41)18-28)33-21-44-35-15-13-25(17-31(33)35)38(52)48-50-40(54)46-29-7-3-5-27(42)19-29/h2-21,36,43-44H,1H3,(H,47,51)(H,48,52)(H2,45,49,53)(H2,46,50,54)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	980	n/a	n/a	n/a	n/a	n/a	n/a
Imam Abdulrahman Bin Faisal University Curated by ChEMBL					Assay Description Inhibition of jack bean urease assessed as reduction in ammonia production using urea as substrate after 15 mins by indophenol method				Bioorg Med Chem 26: 152-160 (2018) Article DOI: 10.1016/j.bmc.2017.11.028 BindingDB Entry DOI: 10.7270/Q22N54VJ
					More data for this Ligand-Target Pair
Urease (Canavalia ensiformis (Jack bean) (Horse bean))	BDBM50452583 (CHEMBL4202456) Show SMILES Cc1ccc(cc1)C(c1c[nH]c2ccc(cc12)C(=O)NNC(=S)Nc1ccc(F)cc1)c1c[nH]c2ccc(cc12)C(=O)NNC(=S)Nc1ccc(F)cc1 Show InChI InChI=1S/C40H32F2N8O2S2/c1-22-2-4-23(5-3-22)36(32-20-43-34-16-6-24(18-30(32)34)37(51)47-49-39(53)45-28-12-8-26(41)9-13-28)33-21-44-35-17-7-25(19-31(33)35)38(52)48-50-40(54)46-29-14-10-27(42)11-15-29/h2-21,36,43-44H,1H3,(H,47,51)(H,48,52)(H2,45,49,53)(H2,46,50,54)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Imam Abdulrahman Bin Faisal University Curated by ChEMBL					Assay Description Inhibition of jack bean urease assessed as reduction in ammonia production using urea as substrate after 15 mins by indophenol method				Bioorg Med Chem 26: 152-160 (2018) Article DOI: 10.1016/j.bmc.2017.11.028 BindingDB Entry DOI: 10.7270/Q22N54VJ
					More data for this Ligand-Target Pair
Beta-glucuronidase (Homo sapiens (Human))	BDBM50284037 (CHEMBL4171949) Show SMILES Cc1ccc(cc1)C(c1c[nH]c2ccc(cc12)C(=O)N\N=C\c1ccc(Cl)cc1Cl)c1c[nH]c2ccc(cc12)C(=O)N\N=C\c1ccc(Cl)cc1Cl Show InChI InChI=1S/C40H28Cl4N6O2/c1-22-2-4-23(5-3-22)38(32-20-45-36-12-8-24(14-30(32)36)39(51)49-47-18-26-6-10-28(41)16-34(26)43)33-21-46-37-13-9-25(15-31(33)37)40(52)50-48-19-27-7-11-29(42)17-35(27)44/h2-21,38,45-46H,1H3,(H,49,51)(H,50,52)/b47-18+,48-19+	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Imam Abdulrahman Bin Faisal University Curated by ChEMBL					Assay Description Inhibition of human beta-glucuronidase				Eur J Med Chem 143: 1757-1767 (2018) Article DOI: 10.1016/j.ejmech.2017.10.071 BindingDB Entry DOI: 10.7270/Q23N25X1
					More data for this Ligand-Target Pair
Beta-glucuronidase (Homo sapiens (Human))	BDBM50284056 (CHEMBL4160327) Show SMILES Cc1ccc(cc1)C(c1c[nH]c2ccc(cc12)C(=O)N\N=C\c1cc(O)ccc1O)c1c[nH]c2ccc(cc12)C(=O)N\N=C\c1cc(O)ccc1O Show InChI InChI=1S/C40H32N6O6/c1-22-2-4-23(5-3-22)38(32-20-41-34-10-6-24(16-30(32)34)39(51)45-43-18-26-14-28(47)8-12-36(26)49)33-21-42-35-11-7-25(17-31(33)35)40(52)46-44-19-27-15-29(48)9-13-37(27)50/h2-21,38,41-42,47-50H,1H3,(H,45,51)(H,46,52)/b43-18+,44-19+	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.14E+3	n/a	n/a	n/a	n/a	n/a	n/a
Imam Abdulrahman Bin Faisal University Curated by ChEMBL					Assay Description Inhibition of human beta-glucuronidase				Eur J Med Chem 143: 1757-1767 (2018) Article DOI: 10.1016/j.ejmech.2017.10.071 BindingDB Entry DOI: 10.7270/Q23N25X1
					More data for this Ligand-Target Pair
Urease (Canavalia ensiformis (Jack bean) (Horse bean))	BDBM50452594 (CHEMBL4216656) Show SMILES Cc1ccc(cc1)C(c1c[nH]c2ccc(cc12)C(=O)NNC(=S)Nc1ccccc1Cl)c1c[nH]c2ccc(cc12)C(=O)NNC(=S)Nc1ccccc1Cl Show InChI InChI=1S/C40H32Cl2N8O2S2/c1-22-10-12-23(13-11-22)36(28-20-43-32-16-14-24(18-26(28)32)37(51)47-49-39(53)45-34-8-4-2-6-30(34)41)29-21-44-33-17-15-25(19-27(29)33)38(52)48-50-40(54)46-35-9-5-3-7-31(35)42/h2-21,36,43-44H,1H3,(H,47,51)(H,48,52)(H2,45,49,53)(H2,46,50,54)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Imam Abdulrahman Bin Faisal University Curated by ChEMBL					Assay Description Inhibition of jack bean urease assessed as reduction in ammonia production using urea as substrate after 15 mins by indophenol method				Bioorg Med Chem 26: 152-160 (2018) Article DOI: 10.1016/j.bmc.2017.11.028 BindingDB Entry DOI: 10.7270/Q22N54VJ
					More data for this Ligand-Target Pair
Beta-glucuronidase (Homo sapiens (Human))	BDBM50284052 (CHEMBL4167523) Show SMILES Cc1ccc(cc1)C(c1c[nH]c2ccc(cc12)C(=O)N\N=C\c1ccccc1F)c1c[nH]c2ccc(cc12)C(=O)N\N=C\c1ccccc1F Show InChI InChI=1S/C40H30F2N6O2/c1-24-10-12-25(13-11-24)38(32-22-43-36-16-14-26(18-30(32)36)39(49)47-45-20-28-6-2-4-8-34(28)41)33-23-44-37-17-15-27(19-31(33)37)40(50)48-46-21-29-7-3-5-9-35(29)42/h2-23,38,43-44H,1H3,(H,47,49)(H,48,50)/b45-20+,46-21+	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Imam Abdulrahman Bin Faisal University Curated by ChEMBL					Assay Description Inhibition of human beta-glucuronidase				Eur J Med Chem 143: 1757-1767 (2018) Article DOI: 10.1016/j.ejmech.2017.10.071 BindingDB Entry DOI: 10.7270/Q23N25X1
					More data for this Ligand-Target Pair
Urease (Canavalia ensiformis (Jack bean) (Horse bean))	BDBM50452580 (CHEMBL4205363) Show SMILES Cc1ccc(cc1)C(c1c[nH]c2ccc(cc12)C(=O)NNC(=S)Nc1ccc(Br)cc1)c1c[nH]c2ccc(cc12)C(=O)NNC(=S)Nc1ccc(Br)cc1 Show InChI InChI=1S/C40H32Br2N8O2S2/c1-22-2-4-23(5-3-22)36(32-20-43-34-16-6-24(18-30(32)34)37(51)47-49-39(53)45-28-12-8-26(41)9-13-28)33-21-44-35-17-7-25(19-31(33)35)38(52)48-50-40(54)46-29-14-10-27(42)11-15-29/h2-21,36,43-44H,1H3,(H,47,51)(H,48,52)(H2,45,49,53)(H2,46,50,54)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Imam Abdulrahman Bin Faisal University Curated by ChEMBL					Assay Description Inhibition of jack bean urease assessed as reduction in ammonia production using urea as substrate after 15 mins by indophenol method				Bioorg Med Chem 26: 152-160 (2018) Article DOI: 10.1016/j.bmc.2017.11.028 BindingDB Entry DOI: 10.7270/Q22N54VJ
					More data for this Ligand-Target Pair
Beta-glucuronidase (Homo sapiens (Human))	BDBM50510743 (CHEMBL4462023) Show SMILES COc1cc(O)ccc1-c1nnc(o1)-c1ccc(cc1)-c1nnc(s1)-c1ccc(O)c(O)c1 Show InChI InChI=1S/C23H16N4O5S/c1-31-19-11-15(28)7-8-16(19)21-25-24-20(32-21)12-2-4-13(5-3-12)22-26-27-23(33-22)14-6-9-17(29)18(30)10-14/h2-11,28-30H,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Imam Abdulrahman Bin Faisal University Curated by ChEMBL					Assay Description Inhibition of human beta-glucuronidase pre-incubated for 30 mins before p-nitrophenyl-beta-D-glucuronide substrate addition by spectrophotometry				Bioorg Med Chem 27: 3145-3155 (2019) Article DOI: 10.1016/j.bmc.2019.05.049 BindingDB Entry DOI: 10.7270/Q2DR2ZVG
					More data for this Ligand-Target Pair
Beta-glucuronidase (Homo sapiens (Human))	BDBM50284079 (CHEMBL4176132) Show SMILES Cc1ccc(cc1)C(c1c[nH]c2ccc(cc12)C(=O)N\N=C\c1ccccc1O)c1c[nH]c2ccc(cc12)C(=O)N\N=C\c1ccccc1O Show InChI InChI=1S/C40H32N6O4/c1-24-10-12-25(13-11-24)38(32-22-41-34-16-14-26(18-30(32)34)39(49)45-43-20-28-6-2-4-8-36(28)47)33-23-42-35-17-15-27(19-31(33)35)40(50)46-44-21-29-7-3-5-9-37(29)48/h2-23,38,41-42,47-48H,1H3,(H,45,49)(H,46,50)/b43-20+,44-21+	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Imam Abdulrahman Bin Faisal University Curated by ChEMBL					Assay Description Inhibition of human beta-glucuronidase				Eur J Med Chem 143: 1757-1767 (2018) Article DOI: 10.1016/j.ejmech.2017.10.071 BindingDB Entry DOI: 10.7270/Q23N25X1
					More data for this Ligand-Target Pair
Urease (Canavalia ensiformis (Jack bean) (Horse bean))	BDBM50452579 (CHEMBL4210263) Show SMILES Cc1ccc(cc1)C(c1c[nH]c2ccc(cc12)C(=O)NNC(=S)Nc1cccc(Br)c1)c1c[nH]c2ccc(cc12)C(=O)NNC(=S)Nc1cccc(Br)c1 Show InChI InChI=1S/C40H32Br2N8O2S2/c1-22-8-10-23(11-9-22)36(32-20-43-34-14-12-24(16-30(32)34)37(51)47-49-39(53)45-28-6-2-4-26(41)18-28)33-21-44-35-15-13-25(17-31(33)35)38(52)48-50-40(54)46-29-7-3-5-27(42)19-29/h2-21,36,43-44H,1H3,(H,47,51)(H,48,52)(H2,45,49,53)(H2,46,50,54)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Imam Abdulrahman Bin Faisal University Curated by ChEMBL					Assay Description Inhibition of jack bean urease assessed as reduction in ammonia production using urea as substrate after 15 mins by indophenol method				Bioorg Med Chem 26: 152-160 (2018) Article DOI: 10.1016/j.bmc.2017.11.028 BindingDB Entry DOI: 10.7270/Q22N54VJ
					More data for this Ligand-Target Pair
Beta-glucuronidase (Homo sapiens (Human))	BDBM50284069 (CHEMBL4162081) Show SMILES COc1ccc(O)c(\C=N\NC(=O)c2ccc3[nH]cc(C(c4c[nH]c5ccc(cc45)C(=O)N\N=C\c4cc(OC)ccc4O)c4ccc(C)cc4)c3c2)c1 Show InChI InChI=1S/C42H36N6O6/c1-24-4-6-25(7-5-24)40(34-22-43-36-12-8-26(18-32(34)36)41(51)47-45-20-28-16-30(53-2)10-14-38(28)49)35-23-44-37-13-9-27(19-33(35)37)42(52)48-46-21-29-17-31(54-3)11-15-39(29)50/h4-23,40,43-44,49-50H,1-3H3,(H,47,51)(H,48,52)/b45-20+,46-21+	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Imam Abdulrahman Bin Faisal University Curated by ChEMBL					Assay Description Inhibition of human beta-glucuronidase				Eur J Med Chem 143: 1757-1767 (2018) Article DOI: 10.1016/j.ejmech.2017.10.071 BindingDB Entry DOI: 10.7270/Q23N25X1
					More data for this Ligand-Target Pair
Beta-glucuronidase (Homo sapiens (Human))	BDBM50284062 (CHEMBL4175388) Show SMILES Cc1ccc(cc1)C(c1c[nH]c2ccc(cc12)C(=O)N\N=C\c1cccc(F)c1)c1c[nH]c2ccc(cc12)C(=O)N\N=C\c1cccc(F)c1 Show InChI InChI=1S/C40H30F2N6O2/c1-24-8-10-27(11-9-24)38(34-22-43-36-14-12-28(18-32(34)36)39(49)47-45-20-25-4-2-6-30(41)16-25)35-23-44-37-15-13-29(19-33(35)37)40(50)48-46-21-26-5-3-7-31(42)17-26/h2-23,38,43-44H,1H3,(H,47,49)(H,48,50)/b45-20+,46-21+	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Imam Abdulrahman Bin Faisal University Curated by ChEMBL					Assay Description Inhibition of human beta-glucuronidase				Eur J Med Chem 143: 1757-1767 (2018) Article DOI: 10.1016/j.ejmech.2017.10.071 BindingDB Entry DOI: 10.7270/Q23N25X1
					More data for this Ligand-Target Pair
Beta-glucuronidase (Homo sapiens (Human))	BDBM50284076 (CHEMBL4165215) Show SMILES Cc1ccc(cc1)C(c1c[nH]c2ccc(cc12)C(=O)N\N=C\c1ccc(O)cc1)c1c[nH]c2ccc(cc12)C(=O)N\N=C\c1ccc(O)cc1 Show InChI InChI=1S/C40H32N6O4/c1-24-2-8-27(9-3-24)38(34-22-41-36-16-10-28(18-32(34)36)39(49)45-43-20-25-4-12-30(47)13-5-25)35-23-42-37-17-11-29(19-33(35)37)40(50)46-44-21-26-6-14-31(48)15-7-26/h2-23,38,41-42,47-48H,1H3,(H,45,49)(H,46,50)/b43-20+,44-21+	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.35E+3	n/a	n/a	n/a	n/a	n/a	n/a
Imam Abdulrahman Bin Faisal University Curated by ChEMBL					Assay Description Inhibition of human beta-glucuronidase				Eur J Med Chem 143: 1757-1767 (2018) Article DOI: 10.1016/j.ejmech.2017.10.071 BindingDB Entry DOI: 10.7270/Q23N25X1
					More data for this Ligand-Target Pair
Urease (Canavalia ensiformis (Jack bean) (Horse bean))	BDBM50452597 (CHEMBL4213332) Show SMILES Cc1ccc(cc1)C(c1c[nH]c2ccc(cc12)C(=O)NNC(=S)Nc1ccccc1Br)c1c[nH]c2ccc(cc12)C(=O)NNC(=S)Nc1ccccc1Br Show InChI InChI=1S/C40H32Br2N8O2S2/c1-22-10-12-23(13-11-22)36(28-20-43-32-16-14-24(18-26(28)32)37(51)47-49-39(53)45-34-8-4-2-6-30(34)41)29-21-44-33-17-15-25(19-27(29)33)38(52)48-50-40(54)46-35-9-5-3-7-31(35)42/h2-21,36,43-44H,1H3,(H,47,51)(H,48,52)(H2,45,49,53)(H2,46,50,54)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Imam Abdulrahman Bin Faisal University Curated by ChEMBL					Assay Description Inhibition of jack bean urease assessed as reduction in ammonia production using urea as substrate after 15 mins by indophenol method				Bioorg Med Chem 26: 152-160 (2018) Article DOI: 10.1016/j.bmc.2017.11.028 BindingDB Entry DOI: 10.7270/Q22N54VJ
					More data for this Ligand-Target Pair
Beta-glucuronidase (Homo sapiens (Human))	BDBM50510746 (CHEMBL4559353) Show SMILES COc1cc(O)ccc1-c1nnc(o1)-c1ccc(cc1)-c1nnc(s1)-c1ccccc1F Show InChI InChI=1S/C23H15FN4O3S/c1-30-19-12-15(29)10-11-17(19)21-26-25-20(31-21)13-6-8-14(9-7-13)22-27-28-23(32-22)16-4-2-3-5-18(16)24/h2-12,29H,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Imam Abdulrahman Bin Faisal University Curated by ChEMBL					Assay Description Inhibition of human beta-glucuronidase pre-incubated for 30 mins before p-nitrophenyl-beta-D-glucuronide substrate addition by spectrophotometry				Bioorg Med Chem 27: 3145-3155 (2019) Article DOI: 10.1016/j.bmc.2019.05.049 BindingDB Entry DOI: 10.7270/Q2DR2ZVG
					More data for this Ligand-Target Pair
Beta-glucuronidase (Homo sapiens (Human))	BDBM50284068 (CHEMBL4167354) Show SMILES COc1ccc(\C=N\NC(=O)c2ccc3[nH]cc(C(c4c[nH]c5ccc(cc45)C(=O)N\N=C\c4ccc(OC)c(O)c4)c4ccc(C)cc4)c3c2)cc1O Show InChI InChI=1S/C42H36N6O6/c1-24-4-8-27(9-5-24)40(32-22-43-34-12-10-28(18-30(32)34)41(51)47-45-20-25-6-14-38(53-2)36(49)16-25)33-23-44-35-13-11-29(19-31(33)35)42(52)48-46-21-26-7-15-39(54-3)37(50)17-26/h4-23,40,43-44,49-50H,1-3H3,(H,47,51)(H,48,52)/b45-20+,46-21+	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.67E+3	n/a	n/a	n/a	n/a	n/a	n/a
Imam Abdulrahman Bin Faisal University Curated by ChEMBL					Assay Description Binding affinity towards HSV-1 thymidine kinase				Eur J Med Chem 143: 1757-1767 (2018) Article DOI: 10.1016/j.ejmech.2017.10.071 BindingDB Entry DOI: 10.7270/Q23N25X1
					More data for this Ligand-Target Pair
Urease (Canavalia ensiformis (Jack bean) (Horse bean))	BDBM50452592 (CHEMBL4217720) Show SMILES Cc1ccc(cc1)C(c1c[nH]c2ccc(cc12)C(=O)NNC(=S)Nc1ccc(Cl)cc1)c1c[nH]c2ccc(cc12)C(=O)NNC(=S)Nc1ccc(Cl)cc1 Show InChI InChI=1S/C40H32Cl2N8O2S2/c1-22-2-4-23(5-3-22)36(32-20-43-34-16-6-24(18-30(32)34)37(51)47-49-39(53)45-28-12-8-26(41)9-13-28)33-21-44-35-17-7-25(19-31(33)35)38(52)48-50-40(54)46-29-14-10-27(42)11-15-29/h2-21,36,43-44H,1H3,(H,47,51)(H,48,52)(H2,45,49,53)(H2,46,50,54)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.75E+3	n/a	n/a	n/a	n/a	n/a	n/a
Imam Abdulrahman Bin Faisal University Curated by ChEMBL					Assay Description Inhibition of jack bean urease assessed as reduction in ammonia production using urea as substrate after 15 mins by indophenol method				Bioorg Med Chem 26: 152-160 (2018) Article DOI: 10.1016/j.bmc.2017.11.028 BindingDB Entry DOI: 10.7270/Q22N54VJ
					More data for this Ligand-Target Pair
Beta-glucuronidase (Homo sapiens (Human))	BDBM50284053 (CHEMBL4174339) Show SMILES Cc1ccc(cc1)C(c1c[nH]c2ccc(cc12)C(=O)N\N=C\c1ccccc1Cl)c1c[nH]c2ccc(cc12)C(=O)N\N=C\c1ccccc1Cl Show InChI InChI=1S/C40H30Cl2N6O2/c1-24-10-12-25(13-11-24)38(32-22-43-36-16-14-26(18-30(32)36)39(49)47-45-20-28-6-2-4-8-34(28)41)33-23-44-37-17-15-27(19-31(33)37)40(50)48-46-21-29-7-3-5-9-35(29)42/h2-23,38,43-44H,1H3,(H,47,49)(H,48,50)/b45-20+,46-21+	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Imam Abdulrahman Bin Faisal University Curated by ChEMBL					Assay Description Inhibition of human beta-glucuronidase				Eur J Med Chem 143: 1757-1767 (2018) Article DOI: 10.1016/j.ejmech.2017.10.071 BindingDB Entry DOI: 10.7270/Q23N25X1
					More data for this Ligand-Target Pair
Beta-glucuronidase (Homo sapiens (Human))	BDBM50284061 (CHEMBL4175788) Show SMILES Cc1ccc(cc1)C(c1c[nH]c2ccc(cc12)C(=O)N\N=C\c1ccc(F)cc1)c1c[nH]c2ccc(cc12)C(=O)N\N=C\c1ccc(F)cc1 Show InChI InChI=1S/C40H30F2N6O2/c1-24-2-8-27(9-3-24)38(34-22-43-36-16-10-28(18-32(34)36)39(49)47-45-20-25-4-12-30(41)13-5-25)35-23-44-37-17-11-29(19-33(35)37)40(50)48-46-21-26-6-14-31(42)15-7-26/h2-23,38,43-44H,1H3,(H,47,49)(H,48,50)/b45-20+,46-21+	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Imam Abdulrahman Bin Faisal University Curated by ChEMBL					Assay Description Inhibition of human beta-glucuronidase				Eur J Med Chem 143: 1757-1767 (2018) Article DOI: 10.1016/j.ejmech.2017.10.071 BindingDB Entry DOI: 10.7270/Q23N25X1
					More data for this Ligand-Target Pair
Beta-glucuronidase (Homo sapiens (Human))	BDBM50284075 (CHEMBL4171988) Show SMILES Cc1ccc(cc1)C(c1c[nH]c2ccc(cc12)C(=O)N\N=C\C=C\c1ccccc1)c1c[nH]c2ccc(cc12)C(=O)N\N=C\C=C\c1ccccc1 Show InChI InChI=1S/C44H36N6O2/c1-30-16-18-33(19-17-30)42(38-28-45-40-22-20-34(26-36(38)40)43(51)49-47-24-8-14-31-10-4-2-5-11-31)39-29-46-41-23-21-35(27-37(39)41)44(52)50-48-25-9-15-32-12-6-3-7-13-32/h2-29,42,45-46H,1H3,(H,49,51)(H,50,52)/b14-8+,15-9+,47-24+,48-25+	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.98E+3	n/a	n/a	n/a	n/a	n/a	n/a
Imam Abdulrahman Bin Faisal University Curated by ChEMBL					Assay Description Inhibition of human beta-glucuronidase				Eur J Med Chem 143: 1757-1767 (2018) Article DOI: 10.1016/j.ejmech.2017.10.071 BindingDB Entry DOI: 10.7270/Q23N25X1
					More data for this Ligand-Target Pair
Urease (Canavalia ensiformis (Jack bean) (Horse bean))	BDBM50452595 (CHEMBL4203333) Show SMILES Cc1ccc(cc1)C(c1c[nH]c2ccc(cc12)C(=O)NNC(=S)Nc1ccccc1C)c1c[nH]c2ccc(cc12)C(=O)NNC(=S)Nc1ccccc1C Show InChI InChI=1S/C42H38N8O2S2/c1-24-12-14-27(15-13-24)38(32-22-43-36-18-16-28(20-30(32)36)39(51)47-49-41(53)45-34-10-6-4-8-25(34)2)33-23-44-37-19-17-29(21-31(33)37)40(52)48-50-42(54)46-35-11-7-5-9-26(35)3/h4-23,38,43-44H,1-3H3,(H,47,51)(H,48,52)(H2,45,49,53)(H2,46,50,54)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Imam Abdulrahman Bin Faisal University Curated by ChEMBL					Assay Description Inhibition of jack bean urease assessed as reduction in ammonia production using urea as substrate after 15 mins by indophenol method				Bioorg Med Chem 26: 152-160 (2018) Article DOI: 10.1016/j.bmc.2017.11.028 BindingDB Entry DOI: 10.7270/Q22N54VJ
					More data for this Ligand-Target Pair
Beta-glucuronidase (Homo sapiens (Human))	BDBM50284070 (CHEMBL4169361) Show SMILES COc1ccc(\C=N\NC(=O)c2ccc3[nH]cc(C(c4c[nH]c5ccc(cc45)C(=O)N\N=C\c4ccc(OC)cc4O)c4ccc(C)cc4)c3c2)c(O)c1 Show InChI InChI=1S/C42H36N6O6/c1-24-4-6-25(7-5-24)40(34-22-43-36-14-10-26(16-32(34)36)41(51)47-45-20-28-8-12-30(53-2)18-38(28)49)35-23-44-37-15-11-27(17-33(35)37)42(52)48-46-21-29-9-13-31(54-3)19-39(29)50/h4-23,40,43-44,49-50H,1-3H3,(H,47,51)(H,48,52)/b45-20+,46-21+	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.45E+3	n/a	n/a	n/a	n/a	n/a	n/a
Imam Abdulrahman Bin Faisal University Curated by ChEMBL					Assay Description Inhibition of human beta-glucuronidase				Eur J Med Chem 143: 1757-1767 (2018) Article DOI: 10.1016/j.ejmech.2017.10.071 BindingDB Entry DOI: 10.7270/Q23N25X1
					More data for this Ligand-Target Pair
Thymidine phosphorylase (Escherichia coli)	BDBM50274861 (CHEMBL4129729) Show SMILES Oc1ccc(-c2nnc(o2)-c2ccc(cc2)C(c2c[nH]c3ccc(Cl)cc23)c2c[nH]c3ccc(Cl)cc23)c(O)c1 Show InChI InChI=1S/C31H20Cl2N4O3/c32-18-5-9-26-22(11-18)24(14-34-26)29(25-15-35-27-10-6-19(33)12-23(25)27)16-1-3-17(4-2-16)30-36-37-31(40-30)21-8-7-20(38)13-28(21)39/h1-15,29,34-35,38-39H	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Imam Abdulrahman Bin Faisal University Curated by ChEMBL					Assay Description Inhibition of Escherichia coli thymidine phosphorylase pretreated for 10 mins followed by substrate addition measured at 10 mins interval for 30 mins...				Bioorg Med Chem 26: 3654-3663 (2018) Article DOI: 10.1016/j.bmc.2018.05.046 BindingDB Entry DOI: 10.7270/Q22V2JKV
					More data for this Ligand-Target Pair
Urease (Canavalia ensiformis (Jack bean) (Horse bean))	BDBM50452586 (CHEMBL4214719) Show SMILES Cc1ccc(NC(=S)NNC(=O)c2ccc3[nH]cc(C(c4c[nH]c5ccc(cc45)C(=O)NNC(=S)Nc4ccc(C)cc4)c4ccc(C)cc4)c3c2)cc1 Show InChI InChI=1S/C42H38N8O2S2/c1-24-4-10-27(11-5-24)38(34-22-43-36-18-12-28(20-32(34)36)39(51)47-49-41(53)45-30-14-6-25(2)7-15-30)35-23-44-37-19-13-29(21-33(35)37)40(52)48-50-42(54)46-31-16-8-26(3)9-17-31/h4-23,38,43-44H,1-3H3,(H,47,51)(H,48,52)(H2,45,49,53)(H2,46,50,54)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Imam Abdulrahman Bin Faisal University Curated by ChEMBL					Assay Description Inhibition of jack bean urease assessed as reduction in ammonia production using urea as substrate after 15 mins by indophenol method				Bioorg Med Chem 26: 152-160 (2018) Article DOI: 10.1016/j.bmc.2017.11.028 BindingDB Entry DOI: 10.7270/Q22N54VJ
					More data for this Ligand-Target Pair
Urease (Canavalia ensiformis (Jack bean) (Horse bean))	BDBM50452585 (CHEMBL4218470) Show SMILES Cc1ccc(cc1)C(c1c[nH]c2ccc(cc12)C(=O)NNC(=S)Nc1cccc(C)c1)c1c[nH]c2ccc(cc12)C(=O)NNC(=S)Nc1cccc(C)c1 Show InChI InChI=1S/C42H38N8O2S2/c1-24-10-12-27(13-11-24)38(34-22-43-36-16-14-28(20-32(34)36)39(51)47-49-41(53)45-30-8-4-6-25(2)18-30)35-23-44-37-17-15-29(21-33(35)37)40(52)48-50-42(54)46-31-9-5-7-26(3)19-31/h4-23,38,43-44H,1-3H3,(H,47,51)(H,48,52)(H2,45,49,53)(H2,46,50,54)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Imam Abdulrahman Bin Faisal University Curated by ChEMBL					Assay Description Inhibition of jack bean urease assessed as reduction in ammonia production using urea as substrate after 15 mins by indophenol method				Bioorg Med Chem 26: 152-160 (2018) Article DOI: 10.1016/j.bmc.2017.11.028 BindingDB Entry DOI: 10.7270/Q22N54VJ
					More data for this Ligand-Target Pair
Beta-glucuronidase (Homo sapiens (Human))	BDBM50510747 (CHEMBL4453038) Show SMILES COc1cc(O)ccc1-c1nnc(o1)-c1ccc(cc1)-c1nnc(s1)-c1ccccc1Cl Show InChI InChI=1S/C23H15ClN4O3S/c1-30-19-12-15(29)10-11-17(19)21-26-25-20(31-21)13-6-8-14(9-7-13)22-27-28-23(32-22)16-4-2-3-5-18(16)24/h2-12,29H,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.14E+3	n/a	n/a	n/a	n/a	n/a	n/a
Imam Abdulrahman Bin Faisal University Curated by ChEMBL					Assay Description Inhibition of human beta-glucuronidase pre-incubated for 30 mins before p-nitrophenyl-beta-D-glucuronide substrate addition by spectrophotometry				Bioorg Med Chem 27: 3145-3155 (2019) Article DOI: 10.1016/j.bmc.2019.05.049 BindingDB Entry DOI: 10.7270/Q2DR2ZVG
					More data for this Ligand-Target Pair
Beta-glucuronidase (Homo sapiens (Human))	BDBM50284063 (CHEMBL4164077) Show SMILES Cc1ccc(cc1)C(c1c[nH]c2ccc(cc12)C(=O)N\N=C\c1ccc(Cl)cc1)c1c[nH]c2ccc(cc12)C(=O)N\N=C\c1ccc(Cl)cc1 Show InChI InChI=1S/C40H30Cl2N6O2/c1-24-2-8-27(9-3-24)38(34-22-43-36-16-10-28(18-32(34)36)39(49)47-45-20-25-4-12-30(41)13-5-25)35-23-44-37-17-11-29(19-33(35)37)40(50)48-46-21-26-6-14-31(42)15-7-26/h2-23,38,43-44H,1H3,(H,47,49)(H,48,50)/b45-20+,46-21+	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Imam Abdulrahman Bin Faisal University Curated by ChEMBL					Assay Description Inhibition of human beta-glucuronidase				Eur J Med Chem 143: 1757-1767 (2018) Article DOI: 10.1016/j.ejmech.2017.10.071 BindingDB Entry DOI: 10.7270/Q23N25X1
					More data for this Ligand-Target Pair
Beta-glucuronidase (Homo sapiens (Human))	BDBM50284074 (CHEMBL4160713) Show SMILES Cc1ccc(cc1)C(c1c[nH]c2ccc(cc12)C(=O)N\N=C\c1cccc(O)c1)c1c[nH]c2ccc(cc12)C(=O)N\N=C\c1cccc(O)c1 Show InChI InChI=1S/C40H32N6O4/c1-24-8-10-27(11-9-24)38(34-22-41-36-14-12-28(18-32(34)36)39(49)45-43-20-25-4-2-6-30(47)16-25)35-23-42-37-15-13-29(19-33(35)37)40(50)46-44-21-26-5-3-7-31(48)17-26/h2-23,38,41-42,47-48H,1H3,(H,45,49)(H,46,50)/b43-20+,44-21+	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.87E+3	n/a	n/a	n/a	n/a	n/a	n/a
Imam Abdulrahman Bin Faisal University Curated by ChEMBL					Assay Description Inhibition of human beta-glucuronidase				Eur J Med Chem 143: 1757-1767 (2018) Article DOI: 10.1016/j.ejmech.2017.10.071 BindingDB Entry DOI: 10.7270/Q23N25X1
					More data for this Ligand-Target Pair
Thymidine phosphorylase (Escherichia coli)	BDBM50274882 (CHEMBL4129587) Show SMILES Oc1ccc(O)c(c1)-c1nnc(o1)-c1ccc(cc1)C(c1c[nH]c2ccc(Cl)cc12)c1c[nH]c2ccc(Cl)cc12 Show InChI InChI=1S/C31H20Cl2N4O3/c32-18-5-8-26-21(11-18)24(14-34-26)29(25-15-35-27-9-6-19(33)12-22(25)27)16-1-3-17(4-2-16)30-36-37-31(40-30)23-13-20(38)7-10-28(23)39/h1-15,29,34-35,38-39H	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Imam Abdulrahman Bin Faisal University Curated by ChEMBL					Assay Description Inhibition of Escherichia coli thymidine phosphorylase pretreated for 10 mins followed by substrate addition measured at 10 mins interval for 30 mins...				Bioorg Med Chem 26: 3654-3663 (2018) Article DOI: 10.1016/j.bmc.2018.05.046 BindingDB Entry DOI: 10.7270/Q22V2JKV
					More data for this Ligand-Target Pair
Beta-glucuronidase (Homo sapiens (Human))	BDBM50510749 (CHEMBL4565724) Show SMILES COc1cc(O)ccc1-c1nnc(o1)-c1ccc(cc1)-c1nnc(s1)-c1cc(O)ccc1O Show InChI InChI=1S/C23H16N4O5S/c1-31-19-11-15(29)6-8-16(19)21-25-24-20(32-21)12-2-4-13(5-3-12)22-26-27-23(33-22)17-10-14(28)7-9-18(17)30/h2-11,28-30H,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Imam Abdulrahman Bin Faisal University Curated by ChEMBL					Assay Description Inhibition of human beta-glucuronidase pre-incubated for 30 mins before p-nitrophenyl-beta-D-glucuronide substrate addition by spectrophotometry				Bioorg Med Chem 27: 3145-3155 (2019) Article DOI: 10.1016/j.bmc.2019.05.049 BindingDB Entry DOI: 10.7270/Q2DR2ZVG
					More data for this Ligand-Target Pair
Beta-glucuronidase (Homo sapiens (Human))	BDBM50284064 (CHEMBL4163659) Show SMILES Cc1ccc(cc1)C(c1c[nH]c2ccc(cc12)C(=O)N\N=C\c1cccc(Cl)c1)c1c[nH]c2ccc(cc12)C(=O)N\N=C\c1cccc(Cl)c1 Show InChI InChI=1S/C40H30Cl2N6O2/c1-24-8-10-27(11-9-24)38(34-22-43-36-14-12-28(18-32(34)36)39(49)47-45-20-25-4-2-6-30(41)16-25)35-23-44-37-15-13-29(19-33(35)37)40(50)48-46-21-26-5-3-7-31(42)17-26/h2-23,38,43-44H,1H3,(H,47,49)(H,48,50)/b45-20+,46-21+	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
Imam Abdulrahman Bin Faisal University Curated by ChEMBL					Assay Description Inhibition of human beta-glucuronidase				Eur J Med Chem 143: 1757-1767 (2018) Article DOI: 10.1016/j.ejmech.2017.10.071 BindingDB Entry DOI: 10.7270/Q23N25X1
					More data for this Ligand-Target Pair
Beta-glucuronidase (Homo sapiens (Human))	BDBM50284078 (CHEMBL4161782) Show SMILES Cc1ccc(cc1)C(c1c[nH]c2ccc(cc12)C(=O)N\N=C\c1cccc(c1)[N+]([O-])=O)c1c[nH]c2ccc(cc12)C(=O)N\N=C\c1cccc(c1)[N+]([O-])=O Show InChI InChI=1S/C40H30N8O6/c1-24-8-10-27(11-9-24)38(34-22-41-36-14-12-28(18-32(34)36)39(49)45-43-20-25-4-2-6-30(16-25)47(51)52)35-23-42-37-15-13-29(19-33(35)37)40(50)46-44-21-26-5-3-7-31(17-26)48(53)54/h2-23,38,41-42H,1H3,(H,45,49)(H,46,50)/b43-20+,44-21+	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.57E+3	n/a	n/a	n/a	n/a	n/a	n/a
Imam Abdulrahman Bin Faisal University Curated by ChEMBL					Assay Description Inhibition of human beta-glucuronidase				Eur J Med Chem 143: 1757-1767 (2018) Article DOI: 10.1016/j.ejmech.2017.10.071 BindingDB Entry DOI: 10.7270/Q23N25X1
					More data for this Ligand-Target Pair
Urease (Canavalia ensiformis (Jack bean) (Horse bean))	BDBM50452581 (CHEMBL4208151) Show SMILES Cc1ccc(cc1)C(c1c[nH]c2ccc(cc12)C(=O)NNC(=S)Nc1cccc(c1)[N+]([O-])=O)c1c[nH]c2ccc(cc12)C(=O)NNC(=S)Nc1cccc(c1)[N+]([O-])=O Show InChI InChI=1S/C40H32N10O6S2/c1-22-8-10-23(11-9-22)36(32-20-41-34-14-12-24(16-30(32)34)37(51)45-47-39(57)43-26-4-2-6-28(18-26)49(53)54)33-21-42-35-15-13-25(17-31(33)35)38(52)46-48-40(58)44-27-5-3-7-29(19-27)50(55)56/h2-21,36,41-42H,1H3,(H,45,51)(H,46,52)(H2,43,47,57)(H2,44,48,58)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	7.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Imam Abdulrahman Bin Faisal University Curated by ChEMBL					Assay Description Inhibition of jack bean urease assessed as reduction in ammonia production using urea as substrate after 15 mins by indophenol method				Bioorg Med Chem 26: 152-160 (2018) Article DOI: 10.1016/j.bmc.2017.11.028 BindingDB Entry DOI: 10.7270/Q22N54VJ
					More data for this Ligand-Target Pair
Beta-glucuronidase (Homo sapiens (Human))	BDBM50510741 (CHEMBL4461536) Show SMILES COc1cc(O)ccc1-c1nnc(o1)-c1ccc(cc1)-c1nnc(s1)-c1ccccc1O Show InChI InChI=1S/C23H16N4O4S/c1-30-19-12-15(28)10-11-17(19)21-25-24-20(31-21)13-6-8-14(9-7-13)22-26-27-23(32-22)16-4-2-3-5-18(16)29/h2-12,28-29H,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	7.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Imam Abdulrahman Bin Faisal University Curated by ChEMBL					Assay Description Inhibition of human beta-glucuronidase pre-incubated for 30 mins before p-nitrophenyl-beta-D-glucuronide substrate addition by spectrophotometry				Bioorg Med Chem 27: 3145-3155 (2019) Article DOI: 10.1016/j.bmc.2019.05.049 BindingDB Entry DOI: 10.7270/Q2DR2ZVG
					More data for this Ligand-Target Pair
Beta-glucuronidase (Homo sapiens (Human))	BDBM50510744 (CHEMBL4570888) Show SMILES COc1cc(O)ccc1-c1nnc(o1)-c1ccc(cc1)-c1nnc(s1)-c1ccc(O)cc1 Show InChI InChI=1S/C23H16N4O4S/c1-30-19-12-17(29)10-11-18(19)21-25-24-20(31-21)13-2-4-14(5-3-13)22-26-27-23(32-22)15-6-8-16(28)9-7-15/h2-12,28-29H,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	8.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Imam Abdulrahman Bin Faisal University Curated by ChEMBL					Assay Description Inhibition of human beta-glucuronidase pre-incubated for 30 mins before p-nitrophenyl-beta-D-glucuronide substrate addition by spectrophotometry				Bioorg Med Chem 27: 3145-3155 (2019) Article DOI: 10.1016/j.bmc.2019.05.049 BindingDB Entry DOI: 10.7270/Q2DR2ZVG
					More data for this Ligand-Target Pair
Urease (Canavalia ensiformis (Jack bean) (Horse bean))	BDBM50452587 (CHEMBL4216067) Show SMILES COc1ccccc1NC(=S)NNC(=O)c1ccc2[nH]cc(C(c3c[nH]c4ccc(cc34)C(=O)NNC(=S)Nc3ccccc3OC)c3ccc(C)cc3)c2c1 Show InChI InChI=1S/C42H38N8O4S2/c1-24-12-14-25(15-13-24)38(30-22-43-32-18-16-26(20-28(30)32)39(51)47-49-41(55)45-34-8-4-6-10-36(34)53-2)31-23-44-33-19-17-27(21-29(31)33)40(52)48-50-42(56)46-35-9-5-7-11-37(35)54-3/h4-23,38,43-44H,1-3H3,(H,47,51)(H,48,52)(H2,45,49,55)(H2,46,50,56)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	8.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Imam Abdulrahman Bin Faisal University Curated by ChEMBL					Assay Description Inhibition of jack bean urease assessed as reduction in ammonia production using urea as substrate after 15 mins by indophenol method				Bioorg Med Chem 26: 152-160 (2018) Article DOI: 10.1016/j.bmc.2017.11.028 BindingDB Entry DOI: 10.7270/Q22N54VJ
					More data for this Ligand-Target Pair
Thymidine phosphorylase (Escherichia coli)	BDBM50274865 (CHEMBL4125852) Show SMILES Fc1ccc(cc1)-c1nnc(o1)-c1ccc(cc1)C(c1c[nH]c2ccc(Cl)cc12)c1c[nH]c2ccc(Cl)cc12 Show InChI InChI=1S/C31H19Cl2FN4O/c32-20-7-11-27-23(13-20)25(15-35-27)29(26-16-36-28-12-8-21(33)14-24(26)28)17-1-3-18(4-2-17)30-37-38-31(39-30)19-5-9-22(34)10-6-19/h1-16,29,35-36H	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Imam Abdulrahman Bin Faisal University Curated by ChEMBL					Assay Description Inhibition of Escherichia coli thymidine phosphorylase pretreated for 10 mins followed by substrate addition measured at 10 mins interval for 30 mins...				Bioorg Med Chem 26: 3654-3663 (2018) Article DOI: 10.1016/j.bmc.2018.05.046 BindingDB Entry DOI: 10.7270/Q22V2JKV
					More data for this Ligand-Target Pair
Thymidine phosphorylase (Escherichia coli)	BDBM50274863 (CHEMBL4126296) Show SMILES Oc1cccc(-c2nnc(o2)-c2ccc(cc2)C(c2c[nH]c3ccc(Cl)cc23)c2c[nH]c3ccc(Cl)cc23)c1O Show InChI InChI=1S/C31H20Cl2N4O3/c32-18-8-10-25-21(12-18)23(14-34-25)28(24-15-35-26-11-9-19(33)13-22(24)26)16-4-6-17(7-5-16)30-36-37-31(40-30)20-2-1-3-27(38)29(20)39/h1-15,28,34-35,38-39H	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Imam Abdulrahman Bin Faisal University Curated by ChEMBL					Assay Description Inhibition of Escherichia coli thymidine phosphorylase pretreated for 10 mins followed by substrate addition measured at 10 mins interval for 30 mins...				Bioorg Med Chem 26: 3654-3663 (2018) Article DOI: 10.1016/j.bmc.2018.05.046 BindingDB Entry DOI: 10.7270/Q22V2JKV
					More data for this Ligand-Target Pair
Urease (Canavalia ensiformis (Jack bean) (Horse bean))	BDBM50452591 (CHEMBL4214615) Show SMILES Cc1ccc(cc1)C(c1c[nH]c2ccc(cc12)C(=O)NNC(=S)Nc1ccc(cc1)[N+]([O-])=O)c1c[nH]c2ccc(cc12)C(=O)NNC(=S)Nc1ccc(cc1)[N+]([O-])=O Show InChI InChI=1S/C40H32N10O6S2/c1-22-2-4-23(5-3-22)36(32-20-41-34-16-6-24(18-30(32)34)37(51)45-47-39(57)43-26-8-12-28(13-9-26)49(53)54)33-21-42-35-17-7-25(19-31(33)35)38(52)46-48-40(58)44-27-10-14-29(15-11-27)50(55)56/h2-21,36,41-42H,1H3,(H,45,51)(H,46,52)(H2,43,47,57)(H2,44,48,58)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	9.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Imam Abdulrahman Bin Faisal University Curated by ChEMBL					Assay Description Inhibition of jack bean urease assessed as reduction in ammonia production using urea as substrate after 15 mins by indophenol method				Bioorg Med Chem 26: 152-160 (2018) Article DOI: 10.1016/j.bmc.2017.11.028 BindingDB Entry DOI: 10.7270/Q22N54VJ
					More data for this Ligand-Target Pair

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